Domo, the main character, is described as "a strange creature that hatched from an egg," with a large, sawtoothed mouth that is locked wide open. Domo's favorite food is Japanese-style meat and potato stew, and he has a strong dislike for apples, because of an unexplained mystery in his DNA. Domo can only communicate by producing a low-pitched noise which sounds somewhat like his own name, but other characters appear to understand him. Domo is known to pass gas repeatedly when nervous or upset. Tokyopop press release of the Domo comic book states that "he communicates sotto voce with a verve that only his friends can understand." Clint Bickham, the writer of the Domo comic book, said that to him Domo's expression is "a sort of cheery wonderment. Like when a kid wakes to a room full of presents on Christmas day." While Domo's face has variants, to Bickham most of his expressions have "an underlying sense of fascination." Friends are Mr.Usaji in Domo and the Bees.